|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (PHPQSNNDQQREGSF) corresponding to the internal amino acids of TET2|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
This antibody is predicted to react with canine and mouse based on sequence homology.
The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.
FLJ20032; KIAA1546; MGC125715; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; tet oncogene family member 2; TET2
KIAA1546; MDS; Nbla00191; TET2