|ChIP assay (ChIP)||5 µg|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 429 and 637 of TET2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.2M tris glycine, pH 7, with 50% glycerol, 1mM EGTA|
|Contains||0.025% ProClin 300|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: KIAA1546; MDS; Methylcytosine dioxygenase TET2; probable methylcytosine dioxygenase TET2; tet methylcytosine dioxygenase 2; tet oncogene family member 2
Gene Aliases: KIAA1546; MDS; Nbla00191; TET2
UniProt ID: (Human) Q6N021
Entrez Gene ID: (Human) 54790
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