Testis-expressed sequence 10 protein (Tex10) functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex. This complex is recruited to ZNF148 by methylated CHTOP leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. Tex10 is also involved in chromatin binding, maturation of LSU-rRNA, regulation of DNA-dependent DNA replication initiation, and rRNA processing.
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Protein Aliases: clone 18330; testis expressed gene 10; Testis-expressed protein 10; testis-expressed sequence 10 protein
Gene Aliases: 2610206N19Rik; 2810462N03Rik; bA208F1.2; BC006867; Ipi1; L18; Nbla10363; TEX10