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Proteintech
TFAP2E Polyclonal Antibody
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Product Details
25829-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TFAP2E Fusion Protein Ag23023 (58-219 aa encoded by BC041175)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: YGQAPDAAA AFPHLAGDPY GGLAPLAQPQ PPQAAWAAPR AAARAHEEPP GLLAPPARAL GLDPRRDYAT AVPRLLHGLA DGAHGLADAP LGLPGLAAAP GLEDLQAMDE PGMSLLDQSV IKKVPIPSKA SSLSALSLAK DSLVGGITNP GEVFCSVPGR LSL (58-219 aa encoded by BC041175)
Target Information
TFAP2E is the sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 epsilon may play a role in the development of the CNS and in cartilage differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: activating enhancer-binding protein 2 epsilon; Activating enhancer-binding protein 2-epsilon; adaptor-related protein complex 2, epsilon subunit; AP2-epsilon; MGC49007; TFAP2E; transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon); Transcription factor AP-2-epsilon
Gene Aliases: AI505200; AP-2e; AP2E; RGD1563297; Tcfap2e; TFAP2E
UniProt ID: (Human) Q6VUC0, (Mouse) Q6VUP9
Entrez Gene ID: (Human) 339488, (Mouse) 332937, (Rat) 313596
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein homodimerization activity
protein heterodimerization activity
DNA binding
transcription factor activity, sequence-specific DNA binding
general transcription factor
transcription from RNA polymerase II promoter
regulation of cell proliferation
positive regulation of transcription from RNA polymerase II promoter
anatomical structure development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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