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Invitrogen
TFAP4 Polyclonal Antibody
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Product Details
PA5-51658
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TFAP4. Recombinant protein control fragment (Product #
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Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: YFMVPTQKVP SLQHFRKTEK EVIGGLCSLA NIPLTPETQR DQERRIRREI ANSNERRRMQ SINAGFQSLK TLIPHTDGEK LSKAAILQQT AEYIFSLEQE KTRLLQQNTQ LKRFIQELSG SSPKRRRAED KDEGIGSPDI WEDEK
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
Transcription factors of the basic helix-loop-helix-zipper(bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activating enhancer-binding protein 4; bHLHc41; Class C basic helix-loop-helix protein 41; Transcription factor AP-4; transcription factor AP-4 (activating enhancer-binding protein 4)
Gene Aliases: AP-4; BHLHC41; TFAP4
UniProt ID: (Human) Q01664
Entrez Gene ID: (Human) 7023
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
protein binding
protein homodimerization activity
histone deacetylase binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
E-box binding
DNA-binding transcription factor
transcription from RNA polymerase II promoter
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
negative regulation of cell proliferation
positive regulation of apoptotic process
negative regulation of DNA binding
negative regulation by host of viral transcription
positive regulation by host of viral transcription
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of cell cycle arrest
cellular response to dexamethasone stimulus
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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