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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide representing a highly antigenic site near the C-terminus of the pS2 protein.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:25-1:50|
|Immunohistochemistry (Paraffin) (IHC (P))||1:25-1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-28875 detects TFF1 from human samples.
PA1-28875 has been successfully used in immunohistochemistry (frozen tissue), immunohistochemistry (paraffin tissue) applications.
The PA1-28875 immunogen is: Synthetic peptide representing a highly antigenic site near the C-terminus of the pS2 protein.
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
BCEI; breast cancer estrogen-inducible protein; breast cancer estrogen-inducible sequence; D21S21; gastrointestinal trefoil protein pS2; HP1.A; HPS2; pNR-2; polypeptide P1.A; protein pS2; pS2
BCEI; D21S21; HP1.A; HPS2; pNR-2; PS2; TFF1