TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
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Protein Aliases: EGF-like TGF; ETGF; Protransforming growth factor alpha; TGF alpha; TGF type 1; TGF-alpha; TGFA; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; waved 1
Gene Aliases: RATTGFAA; TFGA; TGFA; TGFAA; wa-1; wa1