Immunogen sequence: STCTTLDFGH IKKKRVEAIR GQILSKLRLT SPPEPTVMTH VPYQVLALYN STRELLEEMH GEREEGCTQE NTESEYYAKE IHKFDMIQGL AEHNELAVCP KGITSKVFRF NVSSVEKNRT NLFRAEFRVL RVPNPSSKRN EQRIELFQIL RPDEHIAKQR YIGGKNLPTR GTAEWLSFDV TDTVREWLLR RESNLGLEIS IHCPCHTFQP NGDILENIHE VMEIKFKGVD NEDDHGRGDL GRLKKQKDHH NPHLILMMIP PHRLDNPGQG GQRKKR; Positive Samples: BT-474, K-937, Mouse lung, Mouse skeletal muscle, Mouse heart, Rat lung, Rat heart
Transforming growth factor betas (TGFbetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFbetas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule.
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Protein Aliases: LAP; Latency-associated peptide; prepro-transforming growth factor beta-3; TGF-beta-3; Transforming growth factor beta-3; Transforming growth factor beta-3 proprotein; transforming growth factor, beta 3
Gene Aliases: ARVD; ARVD1; LDS5; RNHF; TGF-B3; TGF-beta3; Tgfb-3; TGFB3