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OriGene
TGF beta induced factor 2 Polyclonal Antibody
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FIGURE: 1 / 1
TGF beta induced factor 2 Antibody (TA590467) in WB
Western blot analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Cat # PS100001, Left lane) or pCMV6-ENTRY TGIF2 (Cat # RC200773, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and blotted with anti-TGIF2(Cat # TA590467). Positive lysates [LY411916] (100 µg) and [LC411916] (20 µg) can be purchased separately from OriG... View More
Product Details
TA590467
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DNA immunization. This antibody is specific for the Middle Region of the target protein.
Conjugate
Form
Liquid
Concentration
0.66934 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5'-TG-3' interacting factor 2; 5'-TG-3'-interacting factor 2; Homeobox protein TGIF2; OTTHUMP00000030849; TGF(beta)-induced transcription factor 2; TGF-beta-induced transcription factor 2; TGFB-induced factor 2; TGFB-induced factor 2 (TALE family homeobox); transcription growth factor-beta-induced factor 2; unnamed protein product
Gene Aliases: TGIF2
UniProt ID: (Human) Q9GZN2
Entrez Gene ID: (Human) 60436
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of gastrulation
neuron differentiation
amacrine cell differentiation
nodal signaling pathway
retina development in camera-type eye
positive regulation of amacrine cell differentiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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