Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: SAAWLEKHKKY FALGLLYHYN NQDAAAVQLW VNIVNGDVQD STRSDLYEYI VDFLTYCLDE ELVWAYADWV LQKSEEVGVQ VFTKRPLDEQ QKNSFNPDD
Highest antigen sequence identity to the following orthologs - mouse 88%, rat 90%.
Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: TGF-beta receptor-associated protein 1; Transforming growth factor-beta receptor-associated protein 1; VPS3 CORVET complex subunit
Gene Aliases: TGFBRAP1; TRAP-1; TRAP1; VPS3
UniProt ID: (Human) Q8WUH2
Entrez Gene ID: (Human) 9392
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