This antibody recognizes the endogenous 90 kDa TGM1 proteins.
The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Epidermal TGase; ICR2; K polypeptide; K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase; KTG; LI; LI1; Protein-glutamine gamma-glutamyltransferase K; protein-glutamine-gamma-glutamyltransferase; TG K; TG(K); TGASE; TGase 1; TGase K; TGase-1; TGK; TGM1; Transglutaminase 1; transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase); transglutaminase 1 isoform; transglutaminase 1, K polypeptide; Transglutaminase K; transglutaminase type 1; transglutaminase, keratinocyte; Transglutaminase-1
Gene Aliases: 2310004J08Rik; ARCI1; ICR2; KTG; LI; LI1; TGASE; Tgase1; TGK; TGM1