Immunogen sequence: AGDGTIREGM LVVNGVDLLS SRSDQNRREH HTDEYEYDEL IVRRGQPFHM LLLLSRTYES SDRITLELLI GNNPEVGKGT HVIIPVGKGG SGGWKAQVVK ASGQNLNLRV HTSPNAIIGK FQFTVRTQSD AGEFQLPFDP RNEIYILFNP WCPEDIVYVD HEDWRQEYVL NESGRIYYGT E; Positive Samples: MCF7, 293T; Cellular Location: Lipid-anchor, Membrane
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells.
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Protein Aliases: Epidermal TGase; K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase; Protein-glutamine gamma-glutamyltransferase K; TG(K); TGase K; TGase-1; TGK; transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase); transglutaminase 1 isoform; transglutaminase 1, K polypeptide; Transglutaminase K; transglutaminase, keratinocyte; Transglutaminase-1
Gene Aliases: ARCI1; ICR2; KTG; LI; LI1; TGASE; TGK; TGM1