In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human (rh) TGM2, rhTGM4, and rhTGM7 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle.
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Protein Aliases: E; E polypeptide protein-glutamine-gamma-glutamyltransferase; E polypeptide, protein-glutamine-gamma-glutamyltransferase; MGC126249; MGC126250; Protein-glutamine gamma-glutamyltransferase E; Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain; Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain; TG; TG(E); TGase E; TGase-3; TGE; TGM3; Transglutaminase E; Transglutaminase-3
Gene Aliases: TGE; TGM3
UniProt ID: (Human) Q08188
Entrez Gene ID: (Human) 7053