Immunogen sequence: FNINYNNELP MYRKGTVLIW QKVDEVMTKE IKLPTEMEGK KMAVTRTRTK PVPLHCDIIG DAFWKEHPEI LDEDS
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 76%.
Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ICF45; induced by high glucose-1; Interphase cytoplasmic foci protein 45; Probable tRNA(His) guanylyltransferase; THG1L; tRNA-histidine guanylyltransferase; tRNA-histidine guanylyltransferase 1-like
Gene Aliases: hTHG1; ICF45; IHG-1; THG1L
UniProt ID: (Human) Q9NWX6
Entrez Gene ID: (Human) 54974