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|Tested species reactivity||Human, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (936 DDESGTENREEKDNIQPTTE 955) of THRAP3 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Western Blot (WB)||0.1-1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
THRAP3 is a 955 amino acid novel nuclear receptor and a member of the Thyroid hormone receptor associated proteins with a LISH domain and no obvious known sequence motifs. THRAP3 is a 150 kDa subunit of the large multiprotein complex TRAP and is important in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It is also known to play an important role in transcriptional coactivation. It is known to interact with DKC1, nop5/nap65 and fibrillarin. From the Northern blot analysis of several human tissues it was found that TRAP150 is ubiquitously expressed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
150 kDa subunit; thyroid hormone receptor-associated protein; thyroid hormone receptor-associated protein 3; thyroid hormone receptor-associated protein complex 150 kDa component; thyroid hormone receptor-associated protein, 150 kDa subunit; TRAP150