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Bethyl Laboratories
THRAP3/TRAP150 Polyclonal Antibody
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Product Details
IHC-00158
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residues 905 and the C-terminus (residue 955) of Human Thyroid Hormone Receptor Associated Protein 3 (Thyroid Hormone Receptor-Asscociated Protein, 150 kDa).
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
25 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Gorilla, Chimpanzee and Northern white-cheeked gibbon
Target Information
THRAP3 is a 955 amino acid novel nuclear receptor and a member of the Thyroid hormone receptor associated proteins with a LISH domain and no obvious known sequence motifs. THRAP3 is a 150 kDa subunit of the large multiprotein complex TRAP and is important in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It is also known to play an important role in transcriptional coactivation. It is known to interact with DKC1, nop5/nap65 and fibrillarin. From the Northern blot analysis of several human tissues it was found that TRAP150 is ubiquitously expressed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BCLAF1 and THRAP3 family member 2; Thyroid hormone receptor-associated protein 3; Thyroid hormone receptor-associated protein complex 150 kDa component; thyroid hormone receptor-associated protein, 150 kDa subunit; TR-associated protein, 150-kDa; Trap150
Gene Aliases: BCLAF2; THRAP3; TRAP150
UniProt ID: (Human) Q9Y2W1
Entrez Gene ID: (Human) 9967
regulation of alternative mRNA splicing, via spliceosome
nuclear-transcribed mRNA catabolic process
mRNA processing
circadian rhythm
RNA splicing
positive regulation of circadian rhythm
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of mRNA splicing, via spliceosome
mRNA stabilization
rhythmic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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