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TIGAR Polyclonal Antibody
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FIGURE: 1 / 2
TIGAR Antibody (600-401-FE4) in IHC (P)
Immunohistochemistry of TIGAR antibody. Tissue: Human brain tissue. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: TIGAR antibody at 2.5 µg/mL for 1 hr at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: TIGAR is cytoplasmic. Staining: TIGAR as precipitated red signal with hematoxylin purple nuclear count... View More
Product Details
600-401-FE4
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-TIGAR antibody was prepared from whole rabbit serum produced by repeated immunizations with a 18 amino acid synthetic peptide from near the internal region of human TIGAR.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of the kelch family of proteins, which are characterized by kelch repeat motifs and a POZ/BTB protein-binding domain. It is thought that kelch repeats are actin binding domains. However, the specific function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fructose-2,6-bisphosphatase TIGAR; fructose-2,6-bisphosphate 2-phosphatase; probable fructose-2,6-bisphosphatase TIGAR; TP53-induced glycolysis and apoptosis regulator; TP53-induced glycolysis regulatory phosphatase; transactivated by NS3TP2 protein; unnamed protein product
Gene Aliases: 9630033F20Rik; AA793651; AI595337; C12orf5; C79710; C85509; FR2BP; TIGAR
UniProt ID: (Human) Q9NQ88, (Mouse) Q8BZA9
Entrez Gene ID: (Rat) 502894, (Human) 57103, (Mouse) 319801
response to xenobiotic stimulus
response to gamma radiation
positive regulation of cardiac muscle cell apoptotic process
intestinal epithelial cell development
negative regulation of macromitophagy
negative regulation of reactive oxygen species metabolic process
mitophagy
response to ischemia
fructose 2,6-bisphosphate metabolic process
glycolytic process
autophagy
apoptotic process
response to stress
cellular response to DNA damage stimulus
cardiac muscle cell apoptotic process
glucose catabolic process to lactate via pyruvate
regulation of programmed cell death
negative regulation of programmed cell death
regulation of pentose-phosphate shunt
positive regulation of DNA repair
negative regulation of glycolytic process
positive regulation of nucleobase-containing compound metabolic process
positive regulation of phosphate metabolic process
cellular response to cobalt ion
cellular response to hypoxia
reactive oxygen species metabolic process
regulation of response to DNA damage checkpoint signaling
positive regulation of hexokinase activity
negative regulation of glucose catabolic process to lactate via pyruvate
positive regulation of pentose-phosphate shunt
metabolic process
dephosphorylation
negative regulation of kinase activity
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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