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Invitrogen
TIM-6 Polyclonal Antibody
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Product Details
PA5-148623
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse TIM-6, Glu24-Ala140
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
TIM-6, or T-cell immunoglobulin and mucin-domain containing-6, is a member of the TIM gene family, which plays a significant role in the regulation of immune responses. The TIM family proteins are type I membrane glycoproteins primarily expressed on the surface of various immune cells, including T cells, B cells, and dendritic cells. Although TIM-6 is less well-characterized compared to other members of the TIM family, such as TIM-1, TIM-3, and TIM-4, it is believed to be involved in modulating immune cell interactions and signaling pathways. TIM proteins are known to participate in processes such as T cell activation, tolerance, and the clearance of apoptotic cells. Dysregulation of TIM family proteins has been associated with autoimmune diseases, allergic responses, and cancer, suggesting that TIM-6 may also play a role in these conditions. Understanding the specific functions and mechanisms of TIM-6 within the immune system is crucial for developing potential therapeutic strategies aimed at modulating immune responses in various diseases. Research into TIM-6 can provide valuable insights into the broader roles of the TIM family in immune regulation and their potential as targets for immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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