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          • Primary Antibodies ›
          • TIMM50 Antibodies

          Proteintech

          TIMM50 Polyclonal Antibody

          9 References
          View all (13) TIMM50 antibodies

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          Cite TIMM50 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (10)
          TIMM50 Antibody in Immunocytochemistry (ICC/IF)
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          TIMM50 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 10

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          TIMM50 Antibody (22229-1-AP) in ICC/IF

          Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HepG2 cells using 22229-1-AP (TIMM50 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          TIMM50 Antibody in Immunocytochemistry (ICC/IF)
          TIMM50 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TIMM50 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TIMM50 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TIMM50 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TIMM50 Antibody in Western Blot (WB)
          TIMM50 Antibody in Western Blot (WB)
          TIMM50 Antibody in Western Blot (WB)
          TIMM50 Antibody in Western Blot (WB)
          TIMM50 Antibody in Immunoprecipitation (IP)

          Product Details

          22229-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 5 publications 5 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          View 1 publication 1 publication

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -

          RNA Immunoprecipitation (RIP)

          -
          View 2 publications 2 publications

          Not applicable (N/A)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          TIMM50 Fusion Protein Ag17574 (190-456 aa encoded by BC121147)

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.15 mg/mL

          Amount

          22.5 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: GNNPVDENG AKIPDEFDND PILVQQLRRT YKYFKDYRQM IIEPTSPCLL PDPLQEPYYQ PPYTLVLELT GVLLHPEWSL ATGWRFKKRP GIETLFQQLA PLYEIVIFTS ETGMTAFPLI DSVDPHGFIS YRLFRDATRY MDGHHVKDIS CLNRDPARVV VVDCKKEAFR LQPYNGVALR PWDGNSDDRV LLDLSAFLKT IALNGVEDVR TVLEHYALED DPLAAFKQRQ SRLEQEEQQR LAELSKSNKQ NLFLGSLTSR LWPRSKQP (190-456 aa encoded by BC121147)

          Target Information

          TIMM50 (Mitochondrial import inner membrane translocase subunit TIM50) is an enzyme that in humans is encoded by the TIMM50 gene. Tim50 is a subunit of the Tim23 translocase complex in the inner mitochondrial membrane. Mutations in TIMM50 can lead to epilepsy, severe intellectual disability, and 3-methylglutaconic aciduria. TIMM50 expression is increased in breast cancer cells and decreased in hypertrophic hearts.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: homolog of yeast Tim50; MGC102733; Mitochondrial import inner membrane translocase subunit TIM50; similar to translocase of inner mitochondrial membrane 50 homolog; Tim50-like protein; translocase of inner mitochondrial membrane 50 homolog

          View more View less

          Gene Aliases: 2810403L02Rik; AU015082; MGCA9; PRO1512; TIM50; TIM50L; TIMM50

          View more View less

          UniProt ID: (Human) Q3ZCQ8, (Mouse) Q9D880

          View more View less

          Entrez Gene ID: (Rat) 687295, (Human) 92609, (Mouse) 66525

          View more View less

          Function(s)
          phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity interleukin-2 receptor binding ribonucleoprotein complex binding RNA binding protein binding cysteine-type endopeptidase activator activity
          Process(es)
          release of cytochrome c from mitochondria protein dephosphorylation mitochondrial membrane organization protein transport peptidyl-tyrosine dephosphorylation intracellular protein transport protein import into mitochondrial matrix transport dephosphorylation
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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