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Immunogen sequence: MAELGEADEA ELQRLVAAEQ QKAQFTAQVH HFMELCWDKC VEKPGNRLDS RTENCLSSCV DRFIDTTLAI TSRFAQIVQK GGQ
This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma.
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Protein Aliases: DDP-like protein; Deafness dystonia protein 2; Deafness dystonia protein 2 homolog; Mitochondrial import inner membrane translocase subunit Tim8 B; small zinc finger-like protein DDP2; translocase of inner mitochondrial membrane 8 homolog b
Gene Aliases: DDP2; DDPL; TIM8B; TIMM8B
UniProt ID: (Human) Q9Y5J9, (Mouse) P62077, (Rat) P62078
Entrez Gene ID: (Human) 26521, (Mouse) 30057, (Rat) 64372
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