Recommended positive controls: A431, HeLa.
Predicted reactivity: Mouse (90%), Rat (88%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CC3 (HTATIP2) is a member of the short-chain dehydrogenases/reductases (SDR) family. It is a novel serine/threonine kinase that phosphorylates the C-terminal domain (CTD) of the largest RNA polymerase II subunit and induces the expression of apoptosis related genes Bad and Siva, as well as metastasis suppressor NM23-H2. It also interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates ERalpha-mediated c-myc transcription.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 30 kDa HIV-1 TAT-interacting protein; FLJ26963; HIV-1 tat interactive protein 2, 30 kDa homolog; HIV-1 Tat interactive protein 2, 30kDa; HIV-1 TAT-interactive protein 2; HTATIP2; Oxidoreductase HTATIP2; short chain dehydrogenase/reductase family 44U, member 1; Tat-interacting protein (30kD); tat-interacting protein 30 kDa
Gene Aliases: AW111545; CC3; HTATIP2; SDR44U1; TIP30