Peptide sequence: QIQTSRNLDP QPPIEDSPEV NITDVRMTSP PDYRVGDKIA TRKACGLALA
Sequence homology: Dog: 83%; Guinea Pig: 79%; Horse: 77%; Human: 100%; Mouse: 85%; Rabbit: 77%; Rat: 77%
Strong TKTL1 protein expression has been correlated with a certain type of glucose metabolism (aerobic glycolysis; Warburg effect) and to cells which are affected by chronic complications of diabetic patients. In colon and urothelial carcinomas, expression at the protein level is correlated with invasiveness of tumors and poor patient survival.
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Protein Aliases: TK 2; TKR; TKT2; tktl1; Transketolase 2; transketolase-2; Transketolase-like 1; Transketolase-like protein 1; Transketolase-related protein
Gene Aliases: C79967; TKR; TKT2; TKTL1