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Proteintech
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Immunogen sequence: IESQIQTNEN LIPKSPVEDS PQISVTDIKM TSPHAYKVGD KIATQKTYGL ALAKLGRANE RVIVLSGDTM NSTFSEIFRK EHPERFIECI IAEQNMVSVA LGCATRGRTI AFAGAFAAFF TRAFDQLRMG AISQANINLI GSHCGVSTGE DGVSQMALED LAMFRSIPNC TVFYPSDAIS TEHAIYLAAN TKGMCFIRTS QPETAVIYTP QENFEIGQAK VVRHGVNDKV TVIGAGVTLH EALEAADHLS QQGISVRVID PFTIKPLDAA TIISSAKATG GRVITVEDHY REGGIGEAVC AAVSREPDIL VHQLAVSGVP QRGKTSELLD MFGISTRHII AAVTLTLMK
Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: testis tissue sperm-binding protein Li 39a; transketolase-like 2; Transketolase-like protein 2
Gene Aliases: 4933401I19Rik; RGD1304767; TKTL2
UniProt ID: (Human) Q9H0I9, (Mouse) Q9D4D4
Entrez Gene ID: (Human) 84076, (Rat) 290685, (Mouse) 74419
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