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Proteintech
TLK1 Polyclonal Antibody
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Product Details
13564-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TLK1 Fusion Protein Ag4440 (456-766 aa encoded by BC032657)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: YLLLHLLGR GGFSEVYKAF DLYEQRYAAV KIHQLNKSWR DEKKENYHKH ACREYRIHKE LDHPRIVKLY DYFSLDTDTF CTVLEYCEGN DLDFYLKQHK LMSEKEARSI VMQIVNALRY LNEIKPPIIH YDLKPGNILL VDGTACGEIK ITDFGLSKIM DDDSYGVDGM DLTSQGAGTY WYLPPECFVV GKEPPKISNK VDVWSVGVIF FQCLYGRKPF GHNQSQQDIL QENTILKATE VQFPVKPVVS SEAKAFIRRC LAYRKEDRFD VHQLANDPYL LPHMRRSNSS GNLHMAGLTA SPTPPSSSII TY (456-766 aa encoded by BC032657)
Target Information
TLK1 or tousled-like kinase 1 is a nuclear serine/threonine kinase that is potentially involved in the regulation of chromatin assembly. TLK1 is first described in Arabidopsis. TLK1 is a novel target of the DNA damage checkpoint that is rapidly inactivated upon exposure to ionizing radiation (IR) and the inactivation is directly mediated by the S-phase DNA damage checkpoint. The suppression of TLK1 activity after double-strand breaks in the DNA, replication blockade, or low doses of ultraviolet irradiation requires ATM, NBS and CHK1. The Tousled-like kinases, first described in Arabadopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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