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|Tested species reactivity||Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (817 CRAWYLTKWHKTE 829) of TLR13 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1-3 µg/10^6 cells|
|Western Blot (WB)||1-3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
TLR13, also known as Toll like receptor 13, is a member of the Toll-like receptor (TLR) family of transmembrane proteins comprised of multiple copies of leucine rich repeats in the extracellular domain and a TIR domain. The exact function of the 991 amino acid TLR13 protein is yet unknown, but reports suggest that it is closely related to TLR3 and participates in the innate immune response to microbial agents. TLR13 binds to and acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and inflammatory response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AI666735; Gm713; RP23-186F4.4; toll-like receptor 13
AI666735; Gm713; RGD1562655; Tlr13