Product References
Fetuin-A secretion from β-cells leads to accumulation of macrophages in islets, aggravates inflammation and impairs insulin secretion.
Journal of cell science
Mukhuty A,Fouzder C,Kundu R
48-2300 was used in Flow cytometry/Cell sorting to support an association of fetuin-A with islet inflammation and β-cell dysfunction, owing to its role as a key chemoattractant and macrophage polarizing factor.
Mon Nov 01 00:00:00 EDT 2021
Pentoxifylline prevents epileptic seizure via modulating HMGB1/RAGE/TLR4 signalling pathway and improves memory in pentylenetetrazol kindling rats.
Clinical and experimental pharmacology & physiology
Badawi GA,Shokr MM,Zaki HF,Mohamed AF
Published figure using TLR4 polyclonal antibody (Product # 48-2300) in Western Blot
Sun Aug 01 00:00:00 EDT 2021
Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis.
Science translational medicine
Yu J,Zhu C,Wang X,Kim K,Bartolome A,Dongiovanni P,Yates KP,Valenti L,Carrer M,Sadowski T,Qiang L,Tabas I,Lavine JE,Pajvani UB
48-2300 was used in Immunohistochemistry to identify if increased expression of the Notch ligand Jagged1 (JAG1) tracked with Notch activation and nonalcoholic fatty liver disease (NAFLD) activity score (NAS) in human liver biopsy specimens and mouse NASH models.
Wed Jun 23 00:00:00 EDT 2021
hTERT-immortalized gingival fibroblasts respond to cytokines but fail to mimic primary cell responses to Porphyromonas gingivalis.
Scientific reports
Lagosz-Cwik KB,Wielento A,Lipska W,Kantorowicz M,Darczuk D,Kaczmarzyk T,Gibbs S,Potempa J,Grabiec AM
48-2300 was used in Western Blot to determine the usefulness of the recently released hTERT-immortalized GF (TIGF) cell line for studies of host-pathogen interactions.
Mon May 24 00:00:00 EDT 2021
hTERT-immortalized gingival fibroblasts respond to cytokines but fail to mimic primary cell responses to Porphyromonas gingivalis.
Scientific reports
Lagosz-Cwik KB,Wielento A,Lipska W,Kantorowicz M,Darczuk D,Kaczmarzyk T,Gibbs S,Potempa J,Grabiec AM
48-2300 was used in Western Blot to determine the usefulness of the recently released hTERT-immortalized GF (TIGF) cell line for studies of host-pathogen interactions.
Mon May 24 00:00:00 EDT 2021
Suppression of TLR4-MyD88 signaling pathway attenuated chronic mechanical pain in a rat model of endometriosis.
Journal of neuroinflammation
Su W,Cui H,Wu D,Yu J,Ma L,Zhang X,Huang Y,Ma C
48-2300 was used in Western Blot, Immunohistochemistry (PFA fixed) to study the specific role of TLR4 signaling in the pain symptom of endometriosis (EM) remains obscure.
Fri Mar 05 00:00:00 EST 2021
Suppression of TLR4-MyD88 signaling pathway attenuated chronic mechanical pain in a rat model of endometriosis.
Journal of neuroinflammation
Su W,Cui H,Wu D,Yu J,Ma L,Zhang X,Huang Y,Ma C
48-2300 was used in Western Blot, Immunohistochemistry (PFA fixed) to study the specific role of TLR4 signaling in the pain symptom of endometriosis (EM) remains obscure.
Fri Mar 05 00:00:00 EST 2021
Suppression of TLR4-MyD88 signaling pathway attenuated chronic mechanical pain in a rat model of endometriosis.
Journal of neuroinflammation
Su W,Cui H,Wu D,Yu J,Ma L,Zhang X,Huang Y,Ma C
48-2300 was used in Western Blot, Immunohistochemistry (PFA fixed) to study the specific role of TLR4 signaling in the pain symptom of endometriosis (EM) remains obscure.
Fri Mar 05 00:00:00 EST 2021
Suppression of TLR4-MyD88 signaling pathway attenuated chronic mechanical pain in a rat model of endometriosis.
Journal of neuroinflammation
Su W,Cui H,Wu D,Yu J,Ma L,Zhang X,Huang Y,Ma C
48-2300 was used in Western Blot, Immunohistochemistry (PFA fixed) to study the specific role of TLR4 signaling in the pain symptom of endometriosis (EM) remains obscure.
Fri Mar 05 00:00:00 EST 2021
The psychoactive drug of abuse mephedrone differentially disrupts blood-brain barrier properties.
Journal of neuroinflammation
Buzhdygan TP,Rodrigues CR,McGary HM,Khan JA,Andrews AM,Rawls SM,Ramirez SH
48-2300 was used in Western Blot to investigate the effects of the synthetic cathinone, 4-methyl methcathinone (mephedrone), on blood-brain barrier properties.
Mon Mar 01 00:00:00 EST 2021
The psychoactive drug of abuse mephedrone differentially disrupts blood-brain barrier properties.
Journal of neuroinflammation
Buzhdygan TP,Rodrigues CR,McGary HM,Khan JA,Andrews AM,Rawls SM,Ramirez SH
48-2300 was used in Western Blot to investigate the effects of the synthetic cathinone, 4-methyl methcathinone (mephedrone), on blood-brain barrier properties.
Mon Mar 01 00:00:00 EST 2021
Talin1 controls dendritic cell activation by regulating TLR complex assembly and signaling.
The Journal of experimental medicine
Lim TJF,Bunjamin M,Ruedl C,Su IH
48-2300 was used in Western Blotting to investigate the role and mechanism of Talin in regulating skin dendritic cells (DCs) during inflammatory responses.
Mon Aug 03 00:00:00 EDT 2020
TLR5 participates in the TLR4 receptor complex and promotes MyD88-dependent signaling in environmental lung injury.
eLife
Hussain S,Johnson CG,Sciurba J,Meng X,Stober VP,Liu C,Cyphert-Daly JM,Bulek K,Qian W,Solis A,Sakamachi Y,Trempus CS,Aloor JJ,Gowdy KM,Foster WM,Hollingsworth JW,Tighe RM,Li X,Fessler MB,Garantziotis S
Published figure using TLR4 polyclonal antibody (Product # 48-2300) in Immunoprecipitation
Tue Jan 28 00:00:00 EST 2020
TLR5 participates in the TLR4 receptor complex and promotes MyD88-dependent signaling in environmental lung injury.
eLife
Hussain S,Johnson CG,Sciurba J,Meng X,Stober VP,Liu C,Cyphert-Daly JM,Bulek K,Qian W,Solis A,Sakamachi Y,Trempus CS,Aloor JJ,Gowdy KM,Foster WM,Hollingsworth JW,Tighe RM,Li X,Fessler MB,Garantziotis S
Published figure using TLR4 polyclonal antibody (Product # 48-2300) in Immunoprecipitation
Tue Jan 28 00:00:00 EST 2020
Andrographolide mitigates IL‑1β‑induced human nucleus pulposus cells degeneration through the TLR4/MyD88/NF‑κB signaling pathway.
Molecular medicine reports
Zhang L,Chen Q,Wang H,Yang J,Sheng S
Published figure using TLR4 polyclonal antibody (Product # 48-2300) in Western Blot
Sat Dec 01 00:00:00 EST 2018
Brazilian Red Propolis Attenuates Inflammatory Signaling Cascade in LPS-Activated Macrophages.
PloS one
Bueno-Silva B,Kawamoto D,Ando-Suguimoto ES,Alencar SM,Rosalen PL,Mayer MP
48-2300 was used in Western Blotting to evaluate whether Brazilian red propolis attenuates the inflammatory effect of lipopolysaccharide on macrophages, and investigate the underlying mechanisms.
Wed Jul 06 00:00:00 EDT 2016
TLR4 activation promotes podocyte injury and interstitial fibrosis in diabetic nephropathy.
PloS one
Ma J,Chadban SJ,Zhao CY,Chen X,Kwan T,Panchapakesan U,Pollock CA,Wu H
48-2300 was used in immunohistochemistry - paraffin section to examine the contribution of TLR4 to diabetic nephropathy
Fri Jan 09 00:00:00 EST 2015
TLR4 activation promotes podocyte injury and interstitial fibrosis in diabetic nephropathy.
PloS one
Ma J,Chadban SJ,Zhao CY,Chen X,Kwan T,Panchapakesan U,Pollock CA,Wu H
48-2300 was used in immunohistochemistry - paraffin section to examine the contribution of TLR4 to diabetic nephropathy
Fri Jan 09 00:00:00 EST 2015
TLR4 activation promotes podocyte injury and interstitial fibrosis in diabetic nephropathy.
PloS one
Ma J,Chadban SJ,Zhao CY,Chen X,Kwan T,Panchapakesan U,Pollock CA,Wu H
48-2300 was used in immunohistochemistry - paraffin section to examine the contribution of TLR4 to diabetic nephropathy
Fri Jan 09 00:00:00 EST 2015
Vizantin inhibits endotoxin-mediated immune responses via the TLR 4/MD-2 complex.
Journal of immunology (Baltimore, Md. : 1950)
Oda M,Yamamoto H,Shibutani M,Nakano M,Yabiku K,Tarui T,Kameyama N,Shirakawa D,Obayashi S,Watanabe N,Nakase H,Suenaga M,Matsunaga Y,Nagahama M,Takahashi H,Imagawa H,Kurosawa M,Terao Y,Nishizawa M,Sakurai J
48-2300 was used in immunocytochemistry and western blot to investigate the effect of vizantin on endotoxin-mediated immune responses
Sat Nov 01 00:00:00 EDT 2014
Increased TLR4 expression in murine placentas after oral infection with periodontal pathogens.
Placenta
Arce RM,Barros SP,Wacker B,Peters B,Moss K,Offenbacher S
Sun Feb 01 00:00:00 EST 2009
Toll-like receptors TLR4, TLR5 and TLR9 on gastric carcinoma cells: an implication for interaction with Helicobacter pylori.
International journal of medical microbiology : IJMM
Schmausser B,Andrulis M,Endrich S,Müller-Hermelink HK,Eck M
Wed Jun 01 00:00:00 EDT 2005