A suggested positive control is Jurkat cell lysate.
PA5-20187 can be used with blocking peptide PEP-0317.
TLR6 (Toll-like receptor 6) is a member of the toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved and share structural and functional similarities. TLRs recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR6 functionally interacts with TLR2 to mediate cellular response to bacterial lipoproteins.
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Protein Aliases: CD antigen 286; CD286; Toll-like receptor 6
Gene Aliases: CD286; TLR6