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Proteintech
TM7SF3 Polyclonal Antibody
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Product Details
19826-1-AP
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TM7SF3 Fusion Protein Ag13919 (1-295 aa encoded by BC005176)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MGFLQLLVV AVLASEHRVA GAAEVFGNSS EGLIEFSVGK FRYFELNRPF PEEAILHDIS SNVTFLIFQI HSQYQNTTVS FSPTLLSNSS ETGTASGLVF ILRPEQSTCT WYLGTSGIQP VQNMAILLSY SERDPVPGGC NLEFDLDIDP NIYLEYNFFE TTIKFAPANL GYARGVDPPP CDAGTDQDSR WRLQYDVYQY FLPENDLTEE MLLKHLQRMV SVPQVKASAL KVVTLTANDK TSVSFSSLPG QGVIYNVIVW DPFLNTSAAY IPAHTYACSF EAGEGSCASL GRVSSK (1-295 aa encoded by B C005176)
Target Information
The TM7SF3 gene encodes transmembrane 7 superfamily member 3, a protein that is involved in cellular homeostasis and stress responses. TM7SF3 is characterized by its seven transmembrane domains, which contribute to its role in signal transduction across the cell membrane. This gene is expressed in various tissues and has been implicated in regulating cellular growth and survival pathways, proving critical in the context of cellular response to endoplasmic reticulum (ER) stress and maintaining cellular integrity. TM7SF3 modulates processes such as apoptosis and autophagy, particularly under stress conditions, thus influencing both normal physiological processes and pathological states like cancer. Research has shown that TM7SF3 expression can be altered in certain diseases, affecting pathways that govern cell cycle progression and stress adaptation. Understanding the role of TM7SF3 in cellular signaling and stress management can aid in identifying therapeutic targets for conditions characterized by dysfunctional cellular responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NARP1; Seven span transmembrane protein; seven transmembrane protein TM7SF3; Transmembrane 7 superfamily member 3; unnamed protein product
Gene Aliases: 2010003B14Rik; NARP1; TM7SF3
UniProt ID: (Human) Q9NS93, (Mouse) Q9CRG1
Entrez Gene ID: (Human) 51768, (Mouse) 67623
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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