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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 15 amino acid synthetic peptide near the amino terminus of human TMEM106B|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||20 ug/ml|
|Immunofluorescence (IF)||2.5 ug/mL|
|Immunohistochemistry (IHC)||2.5 ug/mL|
|Western Blot (WB)||1 ug/mL|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control is human liver tissue lysate.
PA5-34353 can be used with blocking peptide PEP-1396.
Transmembrane protein 106B (TMEM106B) is a single-pass transmembrane protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual role of TMEM106B, and that of the closely related protein TMEM106A are still undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.