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Modulator of macroautophagy that causes accumulation of autophagosomes under basal conditions and enhances autophagic flux. Represses cell death and promotes long-term clonogenic survival of cells grown in the absence of glucose in a macroautophagy-independent manner. May have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hCG1651476; Modulator of macroautophagy TMEM150B; Protein DRAM-3; Transmembrane protein 150B; Transmembrane protein 224; transmembrane protein LOC284417
Gene Aliases: TMEM150B; TMEM224
UniProt ID: (Human) A6NC51
Entrez Gene ID: (Human) 284417
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