Search
Proteintech
TMEM16A/DOG1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
12652-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TMEM16A/DOG1 Fusion Protein Ag3320 (541-712 aa encoded by BC027590)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Amount
36 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can recognize isoform1 and isoform2 of human ANO1.
Immunogen sequence: LVYLYMYSK NGTMHGFVNH TLSSFNVSDF QNGTAPNDPL DLGYEVQICR YKDYREPPWS ENKYDISKDF WAVLAARLAF VIVFQNLVMF MSDFVDWVIP DIPKDISQEI HKEKVLMVEL FMREEQDKQQ LLETWMEKER QKDEPPCNHH NTKACPDSLG SPAPSHAYHG GVL (541-712 aa encoded by BC027590)
Target Information
DOG-1, the novel marker, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of kit or PDGFR alpha mutation status.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ano1; anoctamin 1, calcium activated chloride channel; Anoctamin-1; AT5G45830; ATDOG1; Ca2+-activated Cl- channel; cacium activated chloride channel; calcium activated chloride channel; DELAY OF GERMINATION 1; Discovered on gastrointestinal stromal tumors protein 1; FLJ10261; GAAS5; germination ability after storage 5; GLUCOSE SENSING QTL 5; GSQ5; K15I22.3; K15I22_3; membrane protein; oral cancer overexpressed 2; Oral cancer overexpressed protein 2; Transmembrane protein 16A; transmembrane protein 16A (eight membrane-spanning domains); Tumor-amplified and overexpressed sequence 2; unnamed protein product
Gene Aliases: ANO1; DOG1; INDMS; MYMY7; ORAOV2; TAOS2; TMEM16A
UniProt ID: (Human) Q5XXA6, (Mouse) Q6P5C6
Entrez Gene ID: (Human) 55107, (Mouse) 101772
receptor binding
calcium activated cation channel activity
intracellular calcium activated chloride channel activity
voltage-gated chloride channel activity
chloride channel activity
protein binding
iodide transmembrane transporter activity
identical protein binding
protein homodimerization activity
metal ion binding
protein dimerization activity
phospholipid scramblase activity
protein heterodimerization activity
transport
ion transport
cation transport
chloride transport
multicellular organism development
regulation of membrane potential
trachea development
cation transmembrane transport
chloride transmembrane transport
phospholipase C-activating G-protein coupled receptor signaling pathway
iodide transport
ion transmembrane transport
cellular response to heat
detection of temperature stimulus involved in sensory perception of pain
mucus secretion
protein localization to membrane
glial cell projection elongation
cellular response to peptide
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support