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Invitrogen
TMEM16B Polyclonal Antibody
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Product Details
PA5-84348
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ANO2. Recombinant protein control fragment (Product #RP-108423).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EPVSLEARLS RMHFHDSQRK VDYVLAYHYR KRGVHLAQGF PGHSLAIVSN GETGKEPHAG GPGDIELGPL DALEEERKEQ REEFEHNLM
Highest antigen sequence indentity to the following orthologs: Mouse - 84%, Rat - 85%.
Target Information
Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC's include the transmembrane proteins TMEM16A and TMEM16B. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC's but has different biophysical characteristics such as voltage dependence and unitary conductance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: anoctamin 2, calcium activated chloride channel; Anoctamin-2; Transmembrane protein 16B; transmembrane protein 16B (eight membrane-spanning domains)
Gene Aliases: ANO2; C12orf3; TMEM16B
UniProt ID: (Human) Q9NQ90
Entrez Gene ID: (Human) 57101
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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