|Tested species reactivity||Human, Mouse|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human TMEM66|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
TMEM66 is a multi-pass membrane protein which belongs to the TMEM66 family. The exact function of TMEM66 remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Translocation between PI(4,5)P2-poor and PI(4,5)P2-rich microdomains during store depletion determines STIM1 conformation and Orai1 gating.
PA5-24237 was used in western blot to determine STIM1 conformation and Orai1 gating by translocation between PI(4,5)P2-poor and PI(4,5)P2-rich microdomains during store depletion
|Maléth J,Choi S,Muallem S,Ahuja M||Nature communications (5:null)||2014|