Immunogen sequence: RTRKEIEARY LQRKAAKMYT DKLETVPPLN ELTEVPGEDK KKKK
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
This gene encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. This gene is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.