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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||18 amino acid peptide near the carboxy terminus of human TMIGD2|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
|Western Blot (WB)||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A recommended positive control is mouse small intestine tissue lysate.
At least three isoforms of TMIGD2 are known to exist; this antibody will detect all three. TMIGD2 antibody is not expected to cross-react with TMIGD1.
TMIGD2 (transmembrane and immunoglobulin domain containing 1), also known as immunoglobulin-containing and proline-rich receptor 1 (IGPR1), is novel adhesion molecule that is expressed in multiple tissues, primarily in cells of epithelium and endothelium origins. TMIGD2 is thought to be involved in angiogenesis and regulates cellular morphology, homophilic cell aggregation, and cell-cell interaction. TMIGD2 activity also modulates actin stress fiber formation and focal adhesion and reduces cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD28 homolog; CD28 homologue; IGPR-1; IGPR1; Immunoglobulin and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor-1; Transmembrane and immunoglobulin domain-containing protein 2; transmembrane and immunoglobulin domain-containing protein 2 variant 2; transmembrane and immunoglobulin domain-containing protein 2 variant 3; UNQ3059/PRO9879
CD28H; IGPR-1; IGPR1; TMIGD2; UNQ3059/PRO9879