Immunogen sequence: CQVDQATAWE RLRVKWTKDG AILCQPYITN GSLSLGVCGP QGRLSWQAPS HLTLQLDPVS LNHSGAYVCW AAVEIPELEE AEGNITRLFV DPDDPTQNRN RIA
Highest antigen sequence identity to the following orthologs: Mouse - 23%, Rat - 23%.
TMIGD2 (transmembrane and immunoglobulin domain containing 1), also known as immunoglobulin-containing and proline-rich receptor 1 (IGPR1), is novel adhesion molecule that is expressed in multiple tissues, primarily in cells of epithelium and endothelium origins. TMIGD2 is thought to be involved in angiogenesis and regulates cellular morphology, homophilic cell aggregation, and cell-cell interaction. TMIGD2 activity also modulates actin stress fiber formation and focal adhesion and reduces cell migration.
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Protein Aliases: CD28 homolog; CD28 homologue; IGPR-1; Immunoglobulin and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor-1; Transmembrane and immunoglobulin domain-containing protein 2; transmembrane and immunoglobulin domain-containing protein 2 variant 2; transmembrane and immunoglobulin domain-containing protein 2 variant 3
Gene Aliases: CD28H; IGPR-1; IGPR1; TMIGD2; UNQ3059/PRO9879
UniProt ID: (Human) Q96BF3
Entrez Gene ID: (Human) 126259