PA5-31538 targets Tropomodulin 2 in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.
The PA5-31538 immunogen is recombinant fragment corresponding to a region within amino acids 142 and 351 of Human Tropomodulin 2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described.
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Protein Aliases: N-TMOD; neural tropomodulin; Neuronal tropomodulin; NTMOD; tropomodulin 2 (neuronal); Tropomodulin-2
Gene Aliases: N-TMOD; NTMOD; TMOD2