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Proteintech
TMPRSS2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
14437-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TMPRSS2 Fusion Protein Ag5824 (108-492 aa encoded by BC051839)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.31 mg/mL
Amount
46.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: FMGSKCSNS GIECDSSGTC INPSNWCDGV SHCPGGEDEN RCVRLYGPNF ILQVYSSQRK SWHPVCQDDW NENYGRAACR DMGYKNNFYS SQGIVDDSGS TSFMKLNTSA GNVDIYKKLY HSDACSSKAV VSLRCIACGV NLNSSRQSRI VGGESALPGA WPWQVSLHVQ NVHVCGGSII TPEWIVTAAH CVEKPLNNPW HWTAFAGILR QSFMFYGAGY QVEKVISHPN YDSKTKNNDI ALMKLQKPLT FNDLVKPVCL PNPGMMLQPE QLCWISGWGA TEEKGKTSEV LNAAKVLLIE TQRCNSRYVY DNLITPAMIC AGFLQGNVDS CQGDSGGPLV TSKNNIWWLI GDTSWGSGCA KAYRPGVYGN VMVFTDWIYR QMRADG (108-492 aa encoded by BC051839)
Target Information
TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EC 3.4.219; epitheliasin; FLJ41954; MGC6821; plasmic transmembrane protein X; proteinase; putative protease; serine protease 10; TMPRSS2 homolog; TMPS2; transmembrane protease, serine 2; unnamed protein product
Gene Aliases: D16Ertd61e; PRSS10
UniProt ID: (Human) O15393, (Mouse) Q9JIQ8
Entrez Gene ID: (Human) 7113, (Mouse) 50528, (Rat) 156435
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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