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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • TMPRSS3 Antibodies

          Invitrogen

          TMPRSS3 Polyclonal Antibody

          View all (6) TMPRSS3 antibodies

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          Cite TMPRSS3 Polyclonal Antibody

          • Antibody Testing Data (2)
          TMPRSS3 Antibody in Immunocytochemistry (ICC/IF)
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          TMPRSS3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          TMPRSS3 Antibody (PA5-49817) in ICC/IF

          Immunocytochemical analysis of TMPRSS3 in Hela cells, using TMPRSS3 Polyclonal Antibody (Product # PA5-49817). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          TMPRSS3 Antibody in Immunocytochemistry (ICC/IF)
          TMPRSS3 Antibody in Western Blot (WB)
          TMPRSS3 Polyclonal Antibody

          Product Details

          PA5-49817

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthesized peptide derived from C-terminal of human TMPRSS3.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2635270

          Product Specific Information

          The antibody detects endogenous levels of total TMPRSS3 protein.

          Target Information

          This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: Serine protease TADG-12; Transmembrane protease serine 3; transmembrane proteinase serine 3; Tumor-associated differentially-expressed gene 12 protein

          View more View less

          Gene Aliases: DFNB10; DFNB8; ECHOS1; TADG12; TMPRSS3; UNQ323/PRO382

          View more View less

          UniProt ID: (Human) P57727, (Mouse) Q8K1T0

          View more View less

          Entrez Gene ID: (Human) 64699, (Mouse) 140765

          View more View less

          Function(s)
          serine-type endopeptidase activity scavenger receptor activity sodium channel regulator activity peptidase activity serine-type peptidase activity hydrolase activity serine protease
          Process(es)
          proteolysis cellular sodium ion homeostasis receptor-mediated endocytosis sensory perception of sound
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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