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TMX2 Antibody (PA5-102865) in IHC (P)
Immunohistochemistry analysis of TMX2 in human pancreatic cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with TMX2 polyclonal antibody (Product # PA5-102865) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-102865
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TMX2(Accession Q9Y320), corresponding to amino acid residues L28-M78.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2852249
Product Specific Information
Antibody detects endogenous levels of total TMX2.
Target Information
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell proliferation-inducing gene 26 protein; growth-inhibiting gene 11; protein disulfide isomerase family A, member 12; thioredoxin domain containing 14; Thioredoxin domain-containing protein 14; Thioredoxin-related transmembrane protein 2
Gene Aliases: 2310042M24Rik; AA589631; CGI-31; My009; PDIA12; PIG26; PSEC0045; TMX2; TXNDC14; UNQ237/PRO270
UniProt ID: (Human) Q9Y320, (Mouse) Q9D710
Entrez Gene ID: (Human) 51075, (Mouse) 66958
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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