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Product Details
PA5-116723
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 128-296 of human TMX2 (NP_0570431)
Conjugate
Form
Liquid
Concentration
1.67 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901354
Product Specific Information
Positive Samples: U-251MG, HeLa, HepG2, A-549, Mouse liver, Mouse brain, Rat testis
Immunogen sequence: KPPLYMGPEY IKYFNDKTID EELERDKRVT WIVEFFANWS NDCQSFAPIY ADLSLKYNCT GLNFGKVDVG RYTDVSTRYK VSTSPLTKQL PTLILFQGGK EAMRRPQIDK KGRAVSWTFS EENVIREFNL NELYQRAKKL SKAGDNIPEE QPVASTPTTV SDGENKKDK
Target Information
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell proliferation-inducing gene 26 protein; growth-inhibiting gene 11; protein disulfide isomerase family A, member 12; thioredoxin domain containing 14; Thioredoxin domain-containing protein 14; Thioredoxin-related transmembrane protein 2
Gene Aliases: 2310042M24Rik; AA589631; CGI-31; My009; PDIA12; PIG26; PSEC0045; TMX2; TXNDC14; UNQ237/PRO270
UniProt ID: (Human) Q9Y320, (Rat) Q5XIK2, (Mouse) Q9D710
Entrez Gene ID: (Human) 51075, (Rat) 295701, (Mouse) 66958
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