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Immunogen sequence: ENVIREFNLN ELYQRAKKLS KAGDNIPEEQ PVASTPTTVS DGENKKDK
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 79%.
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cell proliferation-inducing gene 26 protein; growth-inhibiting gene 11; protein disulfide isomerase family A, member 12; Thioredoxin domain-containing protein 14; Thioredoxin-related transmembrane protein 2
Gene Aliases: CGI-31; My009; PDIA12; PIG26; PSEC0045; TMX2; TXNDC14; UNQ237/PRO270
UniProt ID: (Human) Q9Y320
Entrez Gene ID: (Human) 51075
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