Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 3
TNFAIP8L1 Antibody (PA5-103341) in IHC (P)
Immunohistochemistry analysis of TNFAIP8L1 in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with TNFAIP8L1 polyclonal antibody (Product # PA5-103341) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-103341
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TNFAIP8L1(Accession Q8WVP5), corresponding to amino acid residues V29-L79.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2852686
Product Specific Information
Antibody detects endogenous levels of total TNFAIP8L1.
Target Information
Tumor necrosis factor, α-induced protein 8-like 1, also known as TNFα-IP 8L1, is a 186 amino acid protein belonging to the TNFα-IP 8 family. Members of the TNFα-IP 8 family are induced by nuclear factor-κB 9 (NFκB) and tumor necrosis factor (TNF), although induction by TNF is dependent upon NFκB activation. TNFα-IP 8 proteins also act as a negative mediator of apoptosis and may play a role in tumor progression. They suppress TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Oxidative stress regulated gene-beta; Oxidative stress-regulated gene-beta; Oxy-beta; TIPE1; TNF alpha-induced protein 8-like protein 1; TNFAIP8-like protein 1; Tumor necrosis factor alpha-induced protein 8-like protein 1; tumor necrosis factor, alpha induced protein 8 like 1; tumor necrosis factor, alpha-induced protein 8-like 1; tumor necrosis factor, alpha-induced protein 8-like protein 1
Gene Aliases: 2600017J23Rik; TIPE1; TNFAIP8L1
UniProt ID: (Human) Q8WVP5, (Mouse) Q8K288
Entrez Gene ID: (Human) 126282, (Rat) 301131, (Mouse) 66443
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support