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Antibody detects endogenous levels of total TNFAIP8L2.
TNFAIP8L2 - Tumor necrosis factor alpha-induced protein 8-like protein 2 (also known as TIPE2) acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. It is a negative regulator of Toll-like receptor and T-cell receptor functions. TIPE2 prevents hyperresponsiveness of the immune system and maintains immune homeostasis. It inhibits JUN/AP1 and NF-kappa-B activation. TIPE2 also promotes Fas-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: inflammation factor 20; Inflammation factor protein 20; TIPE2; TNF alpha-induced protein 8-like protein 2; TNFAIP8-like protein 2; TP8L2; Tumor necrosis factor alpha-induced protein 8-like protein 2; tumor necrosis factor, alpha induced protein 8 like 2; tumor necrosis factor, alpha-induced protein 8-like 2; tumor necrosis factor, alpha-induced protein 8-like protein 2
Gene Aliases: 1810019A08Rik; AW610835; RGD1310519; TIPE2; TNFAIP8L2
UniProt ID: (Human) Q6P589, (Mouse) Q9D8Y7, (Rat) Q6AYJ8
Entrez Gene ID: (Human) 79626, (Mouse) 69769, (Rat) 310663
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