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Proteintech
TNP1 Polyclonal Antibody
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Product Details
17178-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TNP1 Fusion Protein Ag10890 (1-55 aa encoded by BC029516)
Conjugate
Form
Liquid
Concentration
0.38 mg/mL
Amount
57 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSTSRKLKS HGMRRSKSRS PHKGVKRGGS KRKYRKGNLK SRKRGDDANR NYRSHL (1-55 aa encoded by BC029516)
Target Information
TNP1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines. Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 ). Sequence Note: removed 4 bases from the 5' end that did not align to the reference genome assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Spermatid nuclear transition protein 1; STP-1; Testis-specific basic protein; tnp; TP-1; transition protein 1 (during histone to protamine replacement); unnamed protein product
Gene Aliases: Stp-1; TNP1; Tp-1; TP1
UniProt ID: (Human) P09430, (Rat) P02317, (Mouse) P10856
Entrez Gene ID: (Human) 7141, (Rat) 24839, (Mouse) 21958
single strand break repair
nucleosome disassembly
chromatin remodeling
chromatin silencing
multicellular organism development
spermatogenesis
spermatid development
spermatid nucleus elongation
sexual reproduction
sperm motility
negative regulation of transcription, DNA-templated
spermatid nucleus differentiation
positive regulation of protein processing
cell differentiation
heterochromatin assembly
sperm chromatin decondensation
sperm chromatin condensation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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