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Product Details
CL48817178100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
TNP1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines. Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 ). Sequence Note: removed 4 bases from the 5' end that did not align to the reference genome assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Spermatid nuclear transition protein 1; STP-1; Testis-specific basic protein; tnp; TP-1; transition protein 1 (during histone to protamine replacement)
Gene Aliases: Stp-1; TNP1; Tp-1; TP1
UniProt ID: (Human) P09430, (Rat) P02317, (Mouse) P10856
Entrez Gene ID: (Human) 7141, (Rat) 24839, (Mouse) 21958
single strand break repair
nucleosome disassembly
chromatin remodeling
chromatin silencing
multicellular organism development
spermatogenesis
spermatid development
spermatid nucleus elongation
sexual reproduction
sperm motility
negative regulation of transcription, DNA-templated
spermatid nucleus differentiation
fertilization, exchange of chromosomal proteins
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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