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          • Primary Antibodies ›
          • TNPO1 Antibodies

          Invitrogen

          TNPO1 Polyclonal Antibody

          View all (7) TNPO1 antibodies

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          Cite TNPO1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          TNPO1 Antibody in Western Blot (WB)
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          TNPO1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          TNPO1 Antibody (PA5-97214) in WB

          Western blot analysis of TNPO1 in extracts of various cell lines. Samples were incubated with TNPO1 Polyclonal antibody (Product # PA5-97214) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 1s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          TNPO1 Antibody in Western Blot (WB)
          TNPO1 Polyclonal Antibody

          Product Details

          PA5-97214

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:200-1:1,000
          -

          ELISA (ELISA)

          1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide corresponding to a sequence within amino acids 790-890 of human TNPO1 (NP_0022613)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          2.21 mg/mL

          Amount

          221 µg

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2809016

          Product Specific Information

          Positive Samples: LO2, U-87MG, DU145, HeLa, Mouse kidney, Rat kidney; Cellular Location: Cytoplasm, Nucleus

          Immunogen sequence: CPQEVAPMLQ QFIRPWCTSL RNIRDNEEKD SAFRGICTMI SVNPSGVIQD FIFFCDAVAS WINPKDDLRD MFCKILHGFK NQVGDENWRR FSDQFPLPLK E

          Target Information

          TNPO1 comprises the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: importin 2; importin beta 2; Importin beta-2; karyopherin (importin) beta 2; Karyopherin beta-2; M9 region interaction protein; MAPKAP1; MIP; MSIN1; SAPK 1; SIN-1; SIN1; SIN1g; Transportin-1; unnamed protein product

          View more View less

          Gene Aliases: AU021749; D13Ertd688e; IPO2; KPNB2; MIP; MIP1; TNPO1; TRN

          View more View less

          UniProt ID: (Human) Q92973, (Mouse) Q8BFY9

          View more View less

          Entrez Gene ID: (Human) 3842, (Rat) 309126, (Mouse) 238799

          View more View less

          Function(s)
          RNA binding protein binding nuclear localization sequence binding small GTPase binding nuclear import signal receptor activity Ran GTPase binding poly(A) RNA binding transporter
          Process(es)
          protein import into nucleus intracellular protein transport protein transport transport
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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