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Product Details
PA5-66450
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human TNRC6C
Conjugate
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2664843
Product Specific Information
Immunogen sequence: GGLSVKDPSQS QSRLPQWTHP NSMDNLPSAA SPLEQNPSKH GAIPGGLSIG PPGKSSIDDS YGRYDLIQNS ESPASPPVAV PHSWSRAKSD SDKISNGSSI NWPPEFHPGV
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
Target Information
Plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs). Required for miRNA-dependent translational repression of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ20015; Trinucleotide repeat-containing gene 6C protein
Gene Aliases: KIAA1582; TNRC6C
UniProt ID: (Human) Q9HCJ0
Entrez Gene ID: (Human) 57690
Molecular Function:
RNA metabolism protein
nucleic acid metabolism protein
Wnt signaling pathway, calcium modulating pathway
posttranscriptional gene silencing by RNA
gene silencing by miRNA
miRNA mediated inhibition of translation
phosphatidylinositol-mediated signaling
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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