FIGURE: 1 / 1
Immunogen sequence: GGLSVKDPSQS QSRLPQWTHP NSMDNLPSAA SPLEQNPSKH GAIPGGLSIG PPGKSSIDDS YGRYDLIQNS ESPASPPVAV PHSWSRAKSD SDKISNGSSI NWPPEFHPGV
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
Plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs). Required for miRNA-dependent translational repression of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ20015; Trinucleotide repeat-containing gene 6C protein
Gene Aliases: KIAA1582; TNRC6C
UniProt ID: (Human) Q9HCJ0
Entrez Gene ID: (Human) 57690