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Abnova
TNXB Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
TNXB Antibody (H00007148-D01P) in WB
Western Blot analysis of TNXB expression in transfected 293T cell line (H00007148-T02) by TNXB MaxPab polyclonal antibody.
Lane 1: TNXB transfected lysate(74.00 KDa).
Lane 2: Non-transfected lysate.
Lane 1: TNXB transfected lysate(74.00 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00007148-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TNXB (AAH33740.1, 1 a.a. approximately 673 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MRLSWSVAQG PFDSFVVQYE DTNGQPQALL VDGDQSKILI SGLEPSTPYR FLLYGLHEGK RLGPLSAEGT TGLAPAGQTS EESRPRLSQL SVTDVTTSSL RLNWEAPPGA FDSFLLRFGV PSPSTLEPHP RPLLQRELMV PGTRHSAVLR DLRSGTLYSL TLYGLRGPHK ADSIQGTART LSPVLESPRD LQFSEIRETS AKVNWMPPPS RADSFKVSYL LADGGEPQSV QVDGQARTQK LQGLIPGARY EVTVVSVRGF EESEPLTGFL TTVPDGPTQL RALNLTEGFA VLHWKPPQNP VDTYDVQVTA PGAPPLQAET PGSAVDYPLH DLVLHTNYTA TVRGLRGPNL TSPASITFTT GLEAPRDLEA KEVTPRTALL TWTEPPVRPA GYLLSFHTPG GQNQEILLPG GITSHQLLGL FPSTSYNARL QAMWGQSLLP PVSTSFTTGG LRIPFPRDCG EEMQNGAGAS RTSTIFLNGN RERPLNVFCD METDGGGWLV FQRRMDGQTD FWRDWEDYAH GFGNISGEFW LGNEALHSLT QAGDYSMRVD LRAGDEAVFA QYDSFHVDSA AEYYRLHLEG YHGTAGDSMS YHSGSVFSAR DRDPNSLLIS CAVSYRGAWW YRNCHYANLN GLYGSTVDHQ GVSWYHWKGF EFSVPFTEMK LRPRNFRSPA GGG
Target Information
Tenascin-X (TNXB) is a extracellular matrix glycoprotein predominantly located in the outer reticular lamina of the basement membrane (BM). It interacts with many other ECM proteins and it accelerates collagen fibrillogenesisin vitro. TNXB plays a role in interactions between cell and ECM, antiadhesive effect, inhibiting cell migration, and in maintaining homeostasis of the extracellular matrix. Deficiency of TNXB has been associated with the connective tissue disorder Ehlers-Danlos syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GIG45; growth-inhibiting protein 45; Hexabrachion-like protein; tenascin XB1; tenascin XB2; Tenascin-X; TN-X; TNXB2tenascin XB1; TNXBSTNXTENX; unidentified protein; XB-S; XBTN-X
Gene Aliases: EDS3; EDSCLL; EDSCLL1; HXBL; TENX; TN-X; TNX; TNXB; TNXB1; TNXB2; TNXBS; VUR8; XB; XBS
UniProt ID: (Human) P22105
Entrez Gene ID: (Human) 7148
lipid metabolic process
fatty acid metabolic process
triglyceride metabolic process
cell adhesion
cell-matrix adhesion
positive regulation of cell proliferation
positive regulation of epithelial to mesenchymal transition
actin cytoskeleton organization
regulation of cell adhesion
extracellular matrix organization
collagen fibril organization
regulation of cell migration
neuron projection development
collagen metabolic process
regulation of cell differentiation
regulation of JNK cascade
elastic fiber assembly
cell-cell adhesion
positive regulation of vascular endothelial growth factor signaling pathway
positive regulation of collagen fibril organization
positive regulation of cell fate determination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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