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Keep as concentrated solution.
Predicted reactivity: Mouse (96%), Rat (93%).
Positive Control: Jurkat, Jurkat (10 uM Etoposide treatment for 24hr), Lovo, Lovo (200 ng/ml EGF treatment for 0.5 hr).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: formin binding protein 1-like; Formin-binding protein 1-like; Toca-1; transducer of Cdc42-dependent actin assembly 1; Transducer of Cdc42-dependent actin assembly protein 1
Gene Aliases: C1orf39; FNBP1L; TOCA1
UniProt ID: (Human) Q5T0N5
Entrez Gene ID: (Human) 54874
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